Cardiopulmonary exercise testing and the 2022 definition of pulmonary hypertension.

Habedank D;  DRK Kliniken Berlin Köpenick Berlin Germany.; University Medicine Greifswald Greifswald Germany.
Ittermann T; Kaczmarek S; Stubbe B; Heine A; Obst A; Ewert R;

Pulmonary circulation [Pulm Circ] 2024 Jun 17; Vol. 14 (2), pp. e12398.
Date of Electronic Publication: 2024 Jun 17 (Print Publication: 2024).

Parameters of cardiopulmonary exercise testing significantly discriminate between healthy subjects and patients with pulmonary hypertension (PH), also according to the new 2022 definition of pulmonary hypertension (mean pulmonary arterial pressure mPAP > 20 mmHg). The cut-offs indicating on PH were peakVO 2  ≤ 16.7 mL/min/kg (Youden-Index YI = 0.79), p et CO 2 @AT ≤ 34 mmHg (YI = 0.67), and VE/VCO 2 @AT ≤ 30 (YI = 0.76).