Comparing the Physiological Responses to the 6-Minute Walk Test, Timed Up and Go Test, and Treadmill Cardiopulmonary Exercise Test.

Alves ES; University Centre for Rural Health (UCRH) School of Health Sciences University of Sydney, Lismore, New South Wales, Australia.;
Bellet RN; Sharma P; Balmain BN; Aitken C; Doering T;Orola L; Green A; Paim T; , O’Connor F; Morris NR;

Rehabilitation research and practice [Rehabil Res Pract] 2024 Sep 30; Vol. 2024, pp. 1317817.
Date of Electronic Publication: 2024 Sep 30 (Print Publication: 2024).

Purpose: To compare physiological responses during a treadmill cardiopulmonary exercise test (CPX), 6-minute walk test (6MWT), and timed up and go test (TUGT) in individuals referred for unexplained breathlessness and symptom limited treadmill exercise testing.
Methods: Heart rate (HR), oxygen consumption (V̇O 2 ), carbon dioxide production (V̇CO 2 ), respiratory exchange ratio (RER), minute ventilation (V̇ E ), systolic blood pressure (SBP), and rating of perceived exertion (RPE) were recorded throughout each test.
Results: Each test demonstrated a significant increase ( p < 0.01) in the cardiopulmonary (V̇O 2 , V̇CO 2 and V̇ E , RPE, SBP, and HR) and perceptual (RPE) responses from rest to end exercise. The increase in cardiopulmonary and perceptual responses was greatest for the CPX with significantly smaller responses demonstrated during the 6MWT ( p < 0.01) and even smaller responses for the TUGT ( p < 0.01 vs CPX and 6MWT).
Conclusion: Not surprisingly, the treadmill CPX results is the greatest physiological response in our group. Despite being of short duration, the TUGT results in an increased physiological response.