Hollingsworth K; Yale University School of Medicine, New Haven, Connecticut. USA
Zhao Y; Charchaflieh JG; Carr ZJ

A&A Practice. 20(3):e02160, 2026 Mar 01.

The Duke Activity Status Index (DASI) overestimates peak VO2 compared to
cardiopulmonary exercise testing (CPET). This study examined
anthropometric/demographical differences in 226 participants >60 years old
undergoing submaximal CPET (smCPET). Both sexes overestimated DASI versus
smCPET-derived peak oxygen uptake (VO2; males: 5.9 +/- 7.7 mL kg-1 min-1;
females: 7.2 +/- 7.1, P < .001), with no bias differences (P = .224). Body
mass index (BMI) was a primary predictor (beta = .295, P = .001), showing
progressive overestimation: normal/underweight (4.9 +/- 7.5 mL kg-1
min-1), overweight (4.3 +/- 8.5), obese I (6.4 +/- 6.5), obese II+ (9.2
+/- 6). A correction factor was developed: VO2 corrected = 34.08 + 0.153 x
DASIsum-0.382 x BMI-0.123 x age + 1.962 x (1 for males, 0 for females).