Single-Centre Case Series Assessment of Early Exercise Capacity Data Among Patients Who Received an Alterra Prestent and SAPIEN 3 Valve Placement.

Orr WB; Division of Pediatric Cardiology, University School of Medicine, St. Louis, Missouri, USA.
Colombo JN; Roberts B; Avari Silva JN; Missouri, USA.; Balzer D; Shahanavaz S;

CJC pediatric and congenital heart disease [CJC Pediatr Congenit Heart Dis] 2022 Jun 17; Vol. 1 (4), pp. 193-197.
Date of Electronic Publication: 2022 Jun 17 (Print Publication: 2022).

Previous studies have used cardiopulmonary exercise test (CPET) data to objectively assess physiological changes in patients undergoing percutaneous pulmonary valve implantation. A retrospective review was performed to assess pre- and post-CPET data among patients undergoing Alterra Adaptive Prestent and SAPIEN 3 transcatheter heart valve (Alterra) placement. Of the 7 patients eligible for the study, 5 (71%) were male. The mean age was 22 years (range: 12-49 years). CPET data showed significant ( P  = 0.03) improvement in ventilatory efficiency (V E /V CO2 ) while only 2 (29%) patients had an improvement of percent predicted peak oxygen consumption (V O2 ). These findings suggest favourable haemodynamic changes though further investigation is needed.